San Francisco 49ers Schedule 2022: Opponents, Dates, Times, TV Streams and Final Record Predictions

Last season, the San Francisco 49ers were one field goal from making it to the Super Bowl for the second time in three years. The Niners made mistakes against their division rivals in the fourth quarter of the NFC Championship game after leading the Rams by two touchdowns. In the fourth period, San Francisco gave up 13 straight points to Los Angeles and lost 20-17.

The 49ers still have one significant obstacle to overcome going into the season, even with Jimmy Garoppolo still on the roster and 2021 first-round selection Trey Lance likely prepared to take over. The Niners should still be a good chance to play important games through December, and maybe long beyond that, even with the unresolved internal mess.

San Francisco 49ers
Credits: Niner Noise

However, given that their schedule is among the toughest in the NFL this season, it won’t be too simple. San Francisco will need to defeat the following opponents in order to return to the postseason.

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San Francisco 49ers schedule 2022

Week Date Opponent Kickoff time TV channel
1 Sept. 11 at Chicago Bears 1 p.m. ET Fox
2 Sept. 18 vs. Seattle Seahawks 4:05 p.m. ET Fox
3 Sept. 25 at Denver Broncos 8:20 p.m. ET NBC
4 Oct. 3 vs. Los Angeles Rams 8:15 p.m. ET ESPN
5 Oct. 9 at Carolina Panthers 4:05 p.m. ET CBS
6 Oct. 16 at Atlanta Falcons 1 p.m. ET Fox
7 Oct. 23 vs. Kansas City Chiefs 4:25 p.m. ET Fox
8 Oct. 30 at Los Angeles Rams 4:25 p.m. ET Fox
9 Bye
10 Nov. 13 vs. Los Angeles Chargers 8:20 p.m. NBC
11 Nov. 21 (MNF) Cardinals (at Mexico City) 8:15 p.m. ET ESPN
12 Nov. 27 vs. New Orleans Saints 4:25 p.m. ET Fox
13 Dec. 4 vs. Miami Dolphins 4:05 p.m. ET Fox
14 Dec. 11 vs. Tampa Bay Buccaneers 4:25 p.m. ET Fox
15 Dec. 15 at Seattle Seahawks 8:15 p.m. ET Prime Video
16 Dec. 24 vs. Commanders 4:05 p.m. ET CBS
17 Jan. 1 at Las Vegas Raiders 4:05 p.m. ET Fox
18 Jan. 7/8 vs. Arizona Cardinals TBD TBD

Home Games: Arizona Cardinals, Los Angeles Rams, Seattle Seahawks, Kansas City Chiefs, Los Angeles Chargers, Miami Dolphins, New Orleans Saints, Tampa Bay Buccaneers, Washington Commanders

Away Games: Arizona Cardinals, Seattle Seahawks, Los Angeles Rams, Atlanta Falcons, Carolina Panthers, Chicago Bears, Denver Broncos, Las Vegas Raiders

This season, San Francisco will play a total of five games in primetime. Here’s a full breakdown of the 49ers’ primetime showdowns:

  • Week 3 at Denver Broncos: Sunday Night Football, Sept. 25, 5:20 p.m.
  • Week 4 vs. Los Angeles Rams: Monday Night Football, Oct. 3, 5:15 p.m.
  • Week 10 vs. Los Angeles Chargers: Sunday Night Football, Nov. 13, 5:20 p.m.
  • Week 11 at Arizona Cardinals in Mexico City: Monday Night Football, Nov. 21, 5:15 p.m.
  • Week 15 at Seattle Seahawks: Thursday Night Football, Dec. 15, 5:15 p.m.

San Francisco 49ers

San Francisco 49ers final record prediction

With a.533 opponent winning percentage from the previous season, the 49ers’ schedule for the 2022 campaign is among the toughest in the league. With the Seahawks in turmoil and the Cardinals an enigma following a strong start to the 2021 season, the NFC West may not be as difficult a chore as it has been in the past.

However, the Rams are still the best team in the division and have just won the Super Bowl. The 49ers’ future at quarterback will determine whether they succeed or fail as a club. We predict the 49ers to finish the season 12-5.

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