49ers star WR Deebo Samuel (ankle) likely to miss multiple games

San Francisco 49ers hybrid wide receiver Deebo Samuel likely sustained a high-ankle sprain during the second quarter of Sunday's 35-7 win against the visiting Tampa Bay Buccaneers in Santa Clara, Calif, and will likely miss multiple games. San Francisco coach Kyle Shanahan said Samuel will undergo an MRI exam on the injured left ankle. A high-ankle sprain is typically a 4-to-6 week injury. Samuel was injured after his leg bent awkwardly underneath him while being tackled on a 3-yard run, a play that finished with Tampa Bay recovering his fumble. Samuel attempted to get off the field under his own power before needing the assistance of a cart. An emotional Samuel was in tears as he was taken from the field. Samuel, 26, had four carries for 21 yards and a touchdown and four catches for 43 yards before leaving the game. For the season, Samuel has 54 receptions for 612 yards and two touchdowns and has rushed for 228 yards and three scores. --Field Level Media